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Five New Alzheimer’s Genes Discovered


Five new genes linked to the degenerative condition, Alzheimer’s disease, have been identified by a group of scientists in the United States. Researchers say the discovery of these genes will help develop a drug that will be used to treat people affected with the disease.

The scientists came from 44 different universities, as well as research laboratories in the United States. They have identified the genes through an analysis performed on a genetic data derived from about 54,000 people in the Europe and United States.

Gerard Schellenberg, professor of pathology from University of Pennsylvania and lead author of the study, said the identification of the new Alzheimer’s genes will help improve the knowledge on what causes the disease.

The five new genes discovered include ABCA7, CD2AP, CD33, EPHA1 and MS4A. Previously, there were only four variants of Alzheimer’s genes confirmed by the scientists. Until now, there is no available cure for the condition. Treatment involves small symptomatic relief, but most are palliative in nature.

Moreover, the identification of new genes reinforce the latest theories that certain lipids and cholesterol passing around the brain have particular relationship to the onset of Alzheimer’s disease. The study also suggests that the operation of the immune system in the brain plays a particular role.

Today, there are over 10 genes linked to the disease. Dr. Ausim Azizi, head of neurology department at Temple University School of Medicine, said the genes will not be utilized in predictive tests for patients. Alzheimer’s disease affects people over 65 years old. In America, there are one in eight elderly people affected with the disease.

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