Tag Archive | "new england journal"

Study Says Asthma Pills Were as Effective as Inhaled Drugs


British researchers found out that asthma pills were as effective as inhaled steroids in a study that compared the efficacy of both medications.

Dr. Stanley Musgrove, co-author of the study and a senior research associate at the University of East Anglia in Norwich, said that the asthma pills called leukotriene-receptor antagonists should also be considered as treatment option for any patient.

The oral medication has shown similar cost and effectiveness against inhaled steroids, as well as better treatment compliance, Musgrove said. He also said that the study was intended to be a “pragmatic” trial, which means it closely copies the way patients consume medications in real life.

The study consists of 650 volunteers between the age of 12 and 80 with mild to moderate cases of asthma. They had either insufficient control of asthma or had a disrupted quality life because of the condition’s symptoms. The researchers randomly assigned the volunteers to different groups.

The study found out that asthma pills or leukotriene-receptor antagonists work as well as inhaled corticosteroids when utilized as first-line treatment. It also works as well as long-acting rescue medication when utilized as supplementary treatment.

The effectiveness of the medications was measured mainly through Mini Asthma Quality of Life Questionnaire. Findings of the study are published in the New England Journal of Medicine.

St. John Hospital and Medical Center in Detroit chief of allergy and immonology, Dr. Jennifer Appleyard said the findings confirm that there are several options that can be given to asthma patients, and there is not just one answer for them.

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Stay Slim with More Protein and Fewer Refined Carbs, Researchers Say


Weight-loss gurus may have claimed that increased protein and less refined carbohydrates in the diet can keep a person from gaining weight. However, a team of European researchers confirmed this claim based on the study they have compiled with a number of men, women and their families.

The study, which was published in the New England Journal of Medicine, was conducted by Dr. Thomas Meinert Larsen of the University of Copenhagen and his colleagues. Initially, they had 773 men and women with their families from eight western European countries enrolled in the study.

Each family was arbitrarily assigned with one weight-maintenance diet out of five categories for 26 weeks. One group served as the control with no food restrictions. The rest were assigned various proportions of proteins, fats, and carbohydrates that were categorized as high or low glycemic index, which measures how rapid a food is converted to sugar in the blood.

Some people dropped out of the study, which consist mostly of the group from high protein or low-glycemic index category, as well as the low-protein and high-glycemic group.

548 people completed the study, and among them, only those who consumed a low-protein and high-GI diet gained a remarkable amount of weight.

Meanwhile, the researchers discovered that those people who were included in the high-protein gained one kilogram less than those who were included in the low-protein group. The same happened with the low-glycemic index versus high-glycemic index diet.

Based on the study, among the participants who had lost a minimum of eight percent body weight while on a low-calorie diet, those who followed a maintenance diet high in protein and low in refined carbs for the next six months are the least possible to regain any weight. They were also the least likely to drop out of the study.

According to Dr. David Ludwig, anyone can lessen their calorie intake and lose weight for a short span of time; however, the difficult part is to keep it off. However, he suggests for the people to try this diet at home.

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